Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays

ABSTRACT: We descrive a joint model of transcriptional activation and mRNA accumulation, using estrogen receptor ERα activation in MCF-7 breast cancer cell line, which can be used for inference of transcription rate, RNA processing delay and degradation rate given data from high-throughput sequencing time course experiments.

ORGANISM(S): Homo sapiens

PROVIDER: GSE62789 | GEO | 2015/03/04

SECONDARY ACCESSION(S): PRJNA265118

REPOSITORIES: GEO