Genetic analysis reveals a longevity associated protein modulating endothelial function and angiogenesis

ABSTRACT: Transcriptome analysis in HEK293T transfected with plasmid carrying different isoforms of BPIFB4 gene. This gene was previously associated with exceptional longevity in a GWAS study performed on three different populations. Results indicate an up-regulation of stress response genes and proteostasis genes in HEK293T transfected with plasmid carrying the longevity-associated variant (LAV) of BPIFB4.

ORGANISM(S): Homo sapiens

PROVIDER: GSE63912 | GEO | 2015/06/12

SECONDARY ACCESSION(S): PRJNA269385

REPOSITORIES: GEO