The carbonic anhydrase inhibitor ethoxzolamide inhibits the Mycobacterium tuberculosis PhoPR regulon and Esx-1 secretion and attenuates virulence

ABSTRACT: The purpose of this study was to examine how ethoxzolamide modulates gene M. tuberculosis gene expression at acidic pH. We observed that ethoxzolamide downregulates genes of the PhoPR regulon.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE63917 | GEO | 2015/05/20

SECONDARY ACCESSION(S): PRJNA269492

REPOSITORIES: GEO