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Dataset Information

32

Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes [methylation]


ABSTRACT: Examination of the genome-wide distribution of 5hmC in osteoarthritic chondrocytes compared to normal chondrocytes in order to elucidate the effect on OA-specific gene expression. 5hmC-sequencing was performed and data was compared with microarray gene expression data to identify genes with differential expression between normal and OA chondrocytes that are potentially under epigenetic regulation. Overall design: High-throughput sequencing of 5hmC in 4 normal and 4 OA chondrocyte samples.

INSTRUMENT(S): Illumina HiSeq 2000 (Homo sapiens)

ORGANISM(S): Homo sapiens  

SUBMITTER: Nidhi Bhutani  

PROVIDER: GSE64393 | GEO |

SECONDARY ACCESSION(S): PRJNA270885

REPOSITORIES: GEO

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