Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Aortic microRNA expression in germ-free mice and pathogen-free mice

ABSTRACT: To understand the effect of microbes on microRNAs in aorta, in this study, we examined expression of microRNA in the aorta of male (10 weeks old) germ-free mice and pathogen-free mice (control).

ORGANISM(S): Mus musculus

PROVIDER: GSE64630 | GEO | 2016/09/15

SECONDARY ACCESSION(S): PRJNA271482

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

GNPS 3D Germ Free and Specific Pathogen Free Mice

Project description:A collection of metabolomes from organs of germ free and specific pathogen free mice.

2016-07-20 | MSV000079949 | GNPS

Single-cell RNA-seq of germ-free and specific pathogen-free small intestinal epithelium

Project description:The small intestinal epithelial barrier inputs signals from the gut microbiota in order to balance physiological inflammation and tolerance, and to promote homeostasis. Understanding the dynamic relationship between microbes and intestinal epithelial cells has been a challenge given the cellular heterogeneity associated with the epithelium and the inherent difficulty of isolating and identifying individual cell types. Here, we used single-cell RNA sequencing of small intestinal epithelial cells from germ-free and specific pathogen-free mice to study microbe-epithelium crosstalk at the single cell resolution.

2022-08-15 | GSE195742 | GEO

Sorted HSCs from aged Specific Pathogen Free and germ free mice

Project description:Sorted HSCs from aged Specific Pathogen Free and germ free mice

| PRJNA759251 | ENA

Global hepatic gene expression data from germ free and specific pathogen free male mice.

Project description:Liver clock regulates transcription of hepatic genes in response to feeding. To explore the possibility that the microbiome influences this process, we measured the liver transcriptome in normal mice (Specific Pathogen Free or SPF mice) and compared it to the transcriptome in mice lacking microbiota (Germ Free or GF mice) at different time points over 24h. We used microarrays to detail the global programme of gene expression in liver of GF and SPF 10-12 weeks-old male C57Bl/6 male mice. There are 40 liver samples, each from an individual mouse. The samples are from germ free mice (GF) and specific pathogen free mice (SPF). Mice of both types were sacrificed at four time points: Zeitgeber Time 0, 6, 12, and 18. There are five replicates per condition.

2016-02-20 | E-GEOD-71628 | biostudies-arrayexpress

Global hepatic gene expression data from germ free and specific pathogen free male mice.

2016-02-20 | GSE71628 | GEO

RNA-seq mouse intestines from PN, Germ-free, SPF and Antibiotics-treated mice

Project description:We hypothesized that there were genes involved in the maintenance of intestinal tolerance to commensal bacteria. These genes should meet the following criteria: expressed in intestines, upregulated in the presence of commensal bacteria and downregulated in absence of microbes. To find these genes, we collected small intestines from postnatal mice that neither affected by the bacteria nor by the food, adult mice bred in germ-free or specific pathogen-free conditions, and adult SPF mice treated with antibiotics. We therefore performed bulk RNA sequencing using these cells.

2023-01-01 | E-MTAB-12215 | biostudies-arrayexpress

Organ proteomics of germ free and conventional mice

Project description:A proteomic dataset comparing organ tissue differences between germ-free mice to conventional mice. Additional files include supplementary tables for reanalysis.

2019-05-29 | MSV000083874 | MassIVE

Tissue neutrophil heterogeneity in germ free mice

Project description:Tissue neutrophil heterogeneity in germ free mice

| PRJNA597017 | ENA

Amydala transcriptome changes in germ-free mice

Project description:We sequenced mRNA from 12 samples extracted from mouse amygdala tissue to generate the first amygdala-specific murine transcriptome for germ-free mice (GF), conventionally raised controls (CON) and germ-free mice that have been colonized with normal microbiota from postnatal day 21 (exGF).

2015-07-09 | GSE66828 | GEO

Tissue neutrophil heterogeneity in germ free mice

Project description:Purpose: The goals of this study are to compare bulk RNAseq profiles of tissue neutrophils in germ free mice. Methods: Bulk RNAseq of sorted neutrophils from spleen, blood, lung from spf and germ free mice, using Illumina. The sequence reads that passed quality filters were analyzed at the gene level with RSEM.

2020-09-08 | GSE142432 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data