Dataset Information


Microarray expression profliling of mouse whole spleen tissue after infection with L. monocytogenes

ABSTRACT: The infection with the intracellular pathogen Listerial monocytogenes in mice is well characterized resulting in bacterial colonization of various organs, mediated cellular response, and its role in the subsequent clearace of the bacteria, have been well described. In order to comprehensively describe the course of infection and identify molecular events leading to control of infection, we have undertaken whole organ profiling of the mouse spleen after infection. Keywords: L. monocytogenes infection, spleen, microarray Overall design: 4-5 weeks old female animals were i.v. infected with a sub-lethal dose L. monocytogenes EGDe and total spleen RNA was isolated on consecutive hours from 1-4 and days from 1 to 9 post infection. As control pooled RNA of non-infected spleens were used. For each measurement 2-4 chip technical replicates including 1-2 dye swap experiments have been performed.

INSTRUMENT(S): GSF/IEG mouse 20K array version2

SUBMITTER: Martin Irmler 

PROVIDER: GSE6537 | GEO | 2007-08-01



Dataset's files

Action DRS
GSE6537_RAW.tar Raw
filelist.txt Txt
Items per page:
1 - 2 of 2

Similar Datasets

2009-05-29 | GSE13057 | GEO
2010-06-25 | E-GEOD-13057 | ArrayExpress
1000-01-01 | S-EPMC3720536 | BioStudies
2015-01-01 | S-EPMC4496611 | BioStudies
2009-01-01 | S-EPMC2749683 | BioStudies
2019-01-01 | S-EPMC6861014 | BioStudies
1000-01-01 | S-EPMC3028829 | BioStudies
2020-01-01 | S-EPMC7690591 | BioStudies
2004-01-01 | S-EPMC514476 | BioStudies
2016-09-09 | GSE86601 | GEO