Ontology highlight
ABSTRACT:
INSTRUMENT(S): [E_coli_2] Affymetrix E. coli Genome 2.0 Array
SUBMITTER: Heli Elovaara
PROVIDER: GSE65385 | GEO | 2015-09-30
SECONDARY ACCESSION(S): PRJNA273862
REPOSITORIES: GEO
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PloS one 20151110 11
Escherichia coli amine oxidase (ECAO), encoded by the tynA gene, catalyzes the oxidative deamination of aromatic amines into aldehydes through a well-established mechanism, but its exact biological role is unknown. We investigated the role of ECAO by screening environmental and human isolates for tynA and characterizing a tynA-deletion strain using microarray analysis and biochemical studies. The presence of tynA did not correlate with pathogenicity. In tynA+ Escherichia coli strains, ECAO enabl ...[more]