Dietary and protein-restriction protect against renal ischemia-reperfusion injury in mice

ABSTRACT: During kidney transplantation, ischemia reperfusion injury (IRI) is inevitable and leads to oxidative stress and inflammation. We investigated the role of macronutrients in the effects of dietary restriction on both a phenotypical and transcriptional level, thereby comparing protective and nonprotective diets in search for pathways and regulators involved in the protection against IRI.

ORGANISM(S): Mus musculus

PROVIDER: GSE65656 | GEO | 2017/01/20

SECONDARY ACCESSION(S): PRJNA274625

REPOSITORIES: GEO