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Dietary and protein-restriction protect against renal ischemia-reperfusion injury in mice

ABSTRACT: During kidney transplantation, ischemia reperfusion injury (IRI) is inevitable and leads to oxidative stress and inflammation. We investigated the role of macronutrients in the effects of dietary restriction on both a phenotypical and transcriptional level, thereby comparing protective and nonprotective diets in search for pathways and regulators involved in the protection against IRI.

ORGANISM(S): Mus musculus

PROVIDER: GSE65656 | GEO | 2017/01/20

SECONDARY ACCESSION(S): PRJNA274625

REPOSITORIES: GEO

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Transcriptional analysis of murine kidneys after caloric restriction and hypoxic preconditioning in an ischemia-reperfusion injury model

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