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Gene expression analysis of leukemia-initiating cells of compound URE-/+::Msh2-/- mice

ABSTRACT: Expression profiling of FACS purified Lin-cKit+ cells from compound URE-/+::Msh2-/- mice with AML and control animals

ORGANISM(S): Mus musculus

PROVIDER: GSE65668 | GEO | 2015/09/07

SECONDARY ACCESSION(S): PRJNA274678

REPOSITORIES: GEO

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Gene expression analysis of leukemia-initiating cells of compound URE-/+::Msh2-/- mice

Project description:Expression profiling of FACS purified Lin-cKit+ cells from compound URE-/+::Msh2-/- mice with AML and control animals Analysis of gene expression in Lin-cKit+ cells from three URE-/+::Msh2-/- mice and four wild type controls

2015-09-07 | E-GEOD-65668 | biostudies-arrayexpress

Gene expression analysis of leukemia-initiating cells of preleukemic compound URE-/+::Msh2-/- mice

Project description:Expression profiling of FACS purified Lin-cKit+ cells from preleukemic compound URE-/+::Msh2-/- mice and control animals (two separate pools of 3 mice each)

2015-09-07 | GSE65669 | GEO

Gene expression analysis of leukemia-initiating cells of preleukemic compound URE-/+::Msh2-/- mice

Project description:Expression profiling of FACS purified Lin-cKit+ cells from preleukemic compound URE-/+::Msh2-/- mice and control animals (two separate pools of 3 mice each) Analysis of gene expression in Lin-cKit+ cells from two URE-/+::Msh2-/- mice and wild type control animals (two pools of three animals each)

2015-09-07 | E-GEOD-65669 | biostudies-arrayexpress

Gene expression analysis of leukemia-initiating cells of URE-/+::Msh2-/- mice

Project description:Gene expression analysis of leukemia-initiating cells of URE-/+::Msh2-/- mice

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Msh2-Lynch

Project description:Msh2-Lynch

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WT and inv(16)/KITD816Y granulocyte macrophage progenitor (GMP) cells [mouse]

Project description:WT GMPs (Lin- IL7R- Sca1- ckit+ FcgRhiCD34+) and inv(16)/KITD816Y GMPs (Lin- Sca1- ckit+ CD41- FcgR+ CD150-) were FACS sorted as described in material and methods from supplementary data (Estruch M et al 2020)

2020-11-09 | GSE150158 | GEO

Gene expression analysis of leukemia-initiating cells of URE-/+::Msh2-/- mice

Project description:This SuperSeries is composed of the SubSeries listed below.

2015-09-07 | GSE65671 | GEO

Single-cell RT-PCR analysis of Tgd17 progenitors

Project description:The indicated thymic progenitor population was sorted via FACS and then loaded into a Fluidigm C1 small cell capture chip for single-cell capture, lysis, reverse transcription, and preamplification. Preamplified products were analyzed on a BioMark HD with EvaGreen chemistry. The genes analyzed were selected based on bulk RNA sequencing data and/or prior publications, including genes relevant for gamma/delta T cells and T cell progenitors. B6=C57BL/6J, Rag=B6.Rag1-/-, Tcrd=B6.Tcrd-/-, DN1d=Live/TCRd-/Lin-/CD44+/CD25-/CD24+/cKit-, DN2=Live/TCRd-/Lin-/CD44+/CD25+/cKit+, cKit-=Live/TCRd-/Lin-/CD44+/CD25-/cKit-. Lin=CD3/CD8/CD11b/CD11c/CD19/Gr-1/NK1.1/TCRb/Ter-119 Sample naming nomenclature is as follows: MouseLine_CellPopoulation_DateCaptured_CaptureChamber_CellNumberInChamber

2018-08-21 | GSE118770 | GEO

Gene expression analysis of leukemia-initiating cells of URE-/+::Msh2-/- mice

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-09-07 | E-GEOD-65671 | biostudies-arrayexpress

Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions

Project description:To identify the molecular characterisitics of parallel lineage-biased MPP populations arising from hematopoietic stem cells (HSC) we conducted genome-wide analyses of hematopoietic stem, progenitor and mature myeloid cell populations using Affymetrix Gene ST1.0 arrays. Microarray analysis of 3-5 biological replicates of the indicated hematopoietic populations, isolated by FACS sorting from C57BL/6 mouse BM. Immunophenotypic definitions: Long-term HSC (HSCLT) (Lin-/cKit+/Sca1+/Flk2-/CD48-/CD150+); Short-term HSC (HSCST) (Lin-/cKit+/Sca1+/Flk2-/CD48-/CD150-); MPP2 (Lin-/cKit+/Sca1+/Flk2-/CD48+/CD150+); MPP3 (Lin-/cKit+/Sca1+/Flk2-/CD48+/CD150-); MPP4 (Lin-/cKit+/Sca1+/Flk2+); CMP (Lin-/cKit+/Fc?R-/CD34+); GMP (Lin-/cKit+/Fc?R+/CD34+); Pre-granulocyte (PreGr) (Mac1+/Gr1int); Granulocyte (Gr) (Mac1+/Gr1hi). HSC and GMP samples listed here were also used as controls for our related microarray study GSE48893.

2015-05-05 | E-GEOD-68529 | biostudies-arrayexpress

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