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An integrated analysis of phosphorus starvation responses in the diatom Pheaodactylum tricornutum

ABSTRACT: 48 h and 72 h after P, transcriptional profiles of P-depleted (-P) and P-replete (+P) cultures depletion were integrated with metabolite and physiological data. It resulted in identification of essential metabolic pathway remodeled under P deficiency. The most significant inductions were related to proteins involved in phosphate acquisition and scavenging, such as phosphate transporters, alkaline phosphatases and nucleotidases. P-depleted cells also showed photosynthesis, nitrogen assimilation, and nucleic acid and ribosome biosynthesis. Repression of the Calvin cycle along with induction of cytosolic glycolysis and the pentose phosphate pathway led to carbon reallocation. Furthermore, we observed changes in the lipid composition of P-depleted cultures through degradation of phospholipids and induction of biosynthetic pathways of non-phosphorus containing lipids.

ORGANISM(S): Phaeodactylum tricornutum

PROVIDER: GSE66063 | GEO | 2018/01/31

REPOSITORIES: GEO

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