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MicroRNA and gene expression changes in human cerebral aneurysms [expression array]

ABSTRACT: Cerebral Aneurysm tissues and superficial temporal arteries were compared through RNA-Seq to identify differentially expressed genes, and through microRNA microarray to identify differentially expressed microRNAs. Significant miR:gene pairs were identified for potential microRNA silencing regualtory effects.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE66239 | GEO | 2016/02/24

SECONDARY ACCESSION(S): PRJNA276505

REPOSITORIES: GEO

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MicroRNA and gene expression changes in human cerebral aneurysms [RNA-seq]

Project description:Cerebral Aneurysm tissues and superficial temporal arteries were compared through RNA-Seq to identify differentially expressed genes, and through microRNA microarray to identify differentially expressed microRNAs. Significant miR:gene pairs were identified for potential microRNA silencing regualtory effects. To study differentially expressed genes and microRNAs in cerebral aneurysms, we collected 7 cerebral aneurysm tisses and 10 superficial temporal artery (STA) tisses from 17 individuals. We performed RNA-Seq and microRNA microarray analysis on these samples, and compared them using STA as a control.

2016-02-24 | E-GEOD-66238 | biostudies-arrayexpress

MicroRNA and gene expression changes in human cerebral aneurysms [RNA-seq]

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