Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development

ABSTRACT: Tissue- and cell-type specific regulators of alternative splicing (AS) are an essential layer of posttranscriptional gene regulation necessary for normal cellular function, patterning, and development. Here we report the Paternally Expressed 10 (PEG10) are required for patterning of multiple organs, with loss of PEG10, resulting in increasingly severe phenotypes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE66304 | GEO | 2018/02/24

REPOSITORIES: GEO