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Expression of genes in hepatic progenitor-like cells derived from human iPS cells

ABSTRACT: To analyze stem/progenitor cell function, we purified hepatic progenitor-like cells in human iPS cell culture stimulated with cytokines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE66450 | GEO | 2015/03/04

SECONDARY ACCESSION(S): PRJNA277004

REPOSITORIES: GEO

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Expression of genes in hepatic progenitor-like cells derived from human iPS cells, and cultured progenitor cells

Project description:To analyze stem/progenitor cell function, we purified hepatic progenitor-like cells in human iPS cell culture stimulated with cytokines.

2017-09-26 | GSE103988 | GEO

Expression of genes in hepatic progenitor-like cells derived from human iPS cells

Project description:To analyze stem/progenitor cell function, we purified hepatic progenitor-like cells in human iPS cell culture stimulated with cytokines. Gene expression in CD13+CD133+ cells derived from human iPS cell culture

2015-03-04 | E-GEOD-66450 | biostudies-arrayexpress

Human induced pluripotent stem cell-derived hepatic stellate-like cells (iPS-HSCs) overexpressing LHX2 vs control iPS-HSCs

Project description:Transcriptional profiling of human iPS-HSCs overexpressing LHX2 compared with control iPS-HSCs, which were cocultured with human induced pluripotent stem cell-derived hepatic progenitor cells (iPS-HPCs).

2019-02-14 | GSE122750 | GEO

Expression of genes in hepatic progenitor-like cells derived from human iPS cells, and cultured progenitor cells

Project description:Expression of genes in hepatic progenitor-like cells derived from human iPS cells, and cultured progenitor cells

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IL-4 and IL-13 treatment of murine hepatic progenitor cells

Project description:The goal of this study was to determine the response of murine hepatic progenitor cells to the type 2 cytokines IL-4 and IL-13.

2016-07-08 | GSE70704 | GEO

Genome-wide nucleosome positioning maps from undifferentiated human iPS cells (hIPS) and iPS cells differentiated to neural progenitor cells (NPC).

Project description:We report the application of MNase-seq (Kent, Adams et al. 2011) to construct genome-wide nucleosome maps from human cells. To date, genome-wide changes in chromatin structure that occur during development in human cells have not been investigated widely. We have constructed and compared genome-wide chromatin maps from undifferentiated human iPS cells and and iPS cells differentiated to neural progenitor cells (NPC).

2019-04-24 | GSE117870 | GEO

Expression analysis of neural progenitor cells derived from iPS cells generated from skin fibroblasts and umbilical cord mesenchymal cells

2013-05-06 | GSE46647 | GEO

Expression analysis of neural progenitor cells derived from iPS cells generated from skin fibroblasts and umbilical cord mesenchymal cells

Project description:Investigation of whole genome gene expression level changes in neural progenitor cells derived from iPS cells generated from umbilical cord mesenchymal cells, compared to neural progenitor cells derived from iPS cells generated fromskin fibroblasts. Analyze the difference between neural progenitor cells derived from iPS cells generated from different origins. The method to induce reprogramming of somatic cells and human iPS cells for neural differentiation is described in Cai J, Li W, Su H, Qin D, Yang J, et al. (2010) Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells. J Biol Chem 285: 11227-11234. and Kim DS, Lee JS, Leem JW, Huh YJ, Kim JY, et al. (2010) Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity. Stem Cell Rev 6: 270-281. A two-chip study using total RNA recovered from one neural progenitor cell line derived from iPS cells generated from skin fibroblasts (GZF1C7NSCP3) and one neural progenitor cell line derived from iPS cells generated from umbilical cord mesenchymal cells (VMC2C7NSCP3). No replicates were made. Each chip measures the expression level of 45,033 genes from the two samples with fourteen 60-mer probe pairs (PM/MM) per gene, with three-fold technical redundancy.

2013-05-06 | E-GEOD-46647 | biostudies-arrayexpress

miRNA profile in human cardiac progenitor cells and iPS cells

Project description:miRNA profile in human cardiac progenitor cells and iPS cells

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The transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation

Project description:Located in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all other liver cell types by physical association and / or by producing cytokines and chemokines. In liver disease and folllowing liver transplantation, elevated levels of endotoxin (bacterial lipopolysaccharide: LPS) stimulate HSCs to produce increased amounts of cytokines and chemokines. Transcriptomic analysis of cultured HSCs stimulated with LPS yields a survey of expression changes which potentially modulate the hepatic inflammatory and immune responses.

2013-10-31 | GSE49980 | GEO

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