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DDB2 regulates gene expression in ovarian cancer cell lines

ABSTRACT: DDB2 has been suggested to function as a transcription regulator in various cancer cell lines. We stably overexpressed DDB2 in ovarian cancer cell line A2780-CP70, and compared the gene expression profiles between DDB2-overexpressed and empty vector-transfected cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE66636 | GEO | 2015/05/01

SECONDARY ACCESSION(S): PRJNA277527

REPOSITORIES: GEO

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DDB2 regulates gene expression in ovarian cancer cell lines

Project description:DDB2 has been suggested to function as a transcription regulator in various cancer cell lines. We stably overexpressed DDB2 in ovarian cancer cell line A2780-CP70, and compared the gene expression profiles between DDB2-overexpressed and empty vector-transfected cells. Empty vector and DDB2-expressing vector were transfected into A2780-CP70 separately. The stable transfection clones were selected, and gene expression patterns in these clones were investigated through microarray analysis.

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