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Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a mutant altered in antibiotic production

ABSTRACT: The objective was to analyze the differential expression between the wild strain and the Streptomyces clavuligerus ΔclaR::aac mutant

ORGANISM(S): Streptomyces clavuligerus

PROVIDER: GSE66683 | GEO | 2015/08/05

SECONDARY ACCESSION(S): PRJNA277717

REPOSITORIES: GEO

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Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a mutant altered in antibiotic production

Project description:The objective was to analyze the differential expression between the wild strain and the Streptomyces clavuligerus ΔclaR::aac mutant Six experimental conditions were assayed, two strains (Streptomyces clavuligerus ATCC 27064, S. clavuligerus ΔclaR::aac) in three culture times (22.5h, 46.5h and 60 h). Two biological replicates for each condition.

2015-08-05 | E-GEOD-66683 | biostudies-arrayexpress

Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and mutants altered in the antibiotics production

Project description:The objective is to analyze the differential expression between the wild strain and a ccaR-deleted and oppA2::aph mutants 6 biological conditions were used, three strains in two times (exponential and stationary growth phase; Streptomyces clavuligerus ATCC 27064, S. clavuligerus M-bM-^HM-^FccaR and S. clavuligerus oppA2::aph). Four biological replicates were made for each condition

2014-07-01 | E-GEOD-51435 | biostudies-arrayexpress

Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a pSCL4- S. clavuligerus mutant

Project description:The objective is to analyze the differential expression between the wild strain and a pSCL4- S. clavuligerus mutant Experiment type Expression profiling by array

2017-10-25 | GSE92399 | GEO

Expression data from Streptomyces clavuligerus

Project description:To increase production of the important pharmaceutical compounds, both mutagenesis approaches and rational engineering have been extensively applied. Mutagenesis approaches are most popular in industry, but their effects have not yet been studied very well. Here, we used microarrays to compare the transcriptomes of the S. clavuligerus wild type (ATCC 27064) strain and the DS48802 clavulanic acid high-producer strain, which has been obtained by classical strain improvement (mutagenesis). Streptomyces clavuligerus strains were grown in shake flasks. RNA was extracted after 70h and hybridized to microarrays.

2010-11-10 | E-GEOD-24033 | biostudies-arrayexpress

Transcriptional analysis between Streptomyces clavuligerus::pIB139 and S. clavuligerus::pimM

Project description:The objective was to analyze the differential expression between the control strain and S. clavuligerus::pimM. Experiment type Expression profiling by array

2019-03-01 | GSE87092 | GEO

Transcriptional analysis of a S. clavuligerus oppA2-deleted mutant

Project description:The objective is to analyze the expression level of a Streptomyces clavuligerus oppA2-deleted mutant Experiment type Expression profiling by array

2018-09-26 | GSE99917 | GEO

Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and mutants altered in the antibiotics production

Project description:The objective is to analyze the differential expression between the wild strain and a ccaR-deleted and oppA2::aph mutants

2014-07-01 | GSE51435 | GEO

Streptomyces clavuligerus

Project description:Expression data from Streptomyces clavuligerus

| PRJNA130329 | ENA

Streptomyces clavuligerus

Project description:Transcriptional analysis between Streptomyces clavuligerus::pIB139 and S. clavuligerus::pimM

| PRJNA343478 | ENA

Effect of organic nitrogen on gene expression of clavulanic acid biosynthesis in Streptomyces clavuligerus F613-1

Project description:To investigate the function of organic nitrogen on clavulanic acid biosynthesis in Streptomyces clavuligerus, we established F613-1 strain cells cultured in MH fermentation medium and ML fermentation medium. We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different medium at three time points.

2022-08-25 | GSE211765 | GEO

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