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Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [RNA Bind-N-Seq]

ABSTRACT: The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein, we performed CLIP-seq against Celf1 using the 3B1 antibody, in myoblasts, heart tissue, and muscle tissue.

ORGANISM(S): synthetic construct

PROVIDER: GSE67337 | GEO | 2015/04/13

SECONDARY ACCESSION(S): PRJNA279533

REPOSITORIES: GEO

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Project description:This SuperSeries is composed of the SubSeries listed below.

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