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Expression data of LoVo cells treated by 10mM metformin for eigher 8 or 24h

ABSTRACT: Metformin is effective for prevention or treatment of various tumors. There are a lot of studies on the underlying mechanisms of metformin as respect to its anti-tumor action. We used microarrays to detail the global programme of gene expression underlying the anti-tumor effects of metformin on LoVo cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE67342 | GEO | 2015/03/31

SECONDARY ACCESSION(S): PRJNA279831

REPOSITORIES: GEO

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Expression data of LoVo cells treated by 10mM metformin for eigher 8 or 24h

Project description:Metformin is effective for prevention or treatment of various tumors. There are a lot of studies on the underlying mechanisms of metformin as respect to its anti-tumor action. We used microarrays to detail the global programme of gene expression underlying the anti-tumor effects of metformin on LoVo cells. Human derived LoVo cells were treated with metformin (10mM) for 8 and 24h, and the control and treated cells were harvested for RNA extraction and hybridization on Affymetrix microarrays.The samples were grouped as Met8h, Met24h, Con8h, and Con24h, respectively.

2015-03-31 | E-GEOD-67342 | biostudies-arrayexpress

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