Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The effect of BRG1 on the responsivness of IFNg Stimulated Genes

ABSTRACT: We studied the effect of reconstitution of BRG1 in BRG1-deficient cells on the responsivness of IFNg stimulated genes. Cells were infected with control adenovirus or BRG1-encoding virus. Cells were then left untreated or exposed to IFNg for 6 hours. Total RNA was collected and analyzed with Illumina arrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE67626 | GEO | 2015/05/01

SECONDARY ACCESSION(S): PRJNA280509

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

The effect of BRG1 on the responsivness of IFNg Stimulated Genes

Project description:We studied the effect of reconstitution of BRG1 in BRG1-deficient cells on the responsivness of IFNg stimulated genes. Cells were infected with control adenovirus or BRG1-encoding virus. Cells were then left untreated or exposed to IFNg for 6 hours. Total RNA was collected and analyzed with Illumina arrays. SW13 cells were infected with BRG1-encoding adenovirus or control virus. Cells were left untreated or exposed to IFNg for 6 hours

2015-05-01 | E-GEOD-67626 | biostudies-arrayexpress

The effect of SUZ12 knockdown on the responsivness of IFNg Stimulated Genes

Project description:We studied the effect of knowking down SUZ12 +/- knowckdown of BRM on the responsivness of IFNg stimulated genes. Cells were transfected with siSZU12+/-siBRM or control siRNA+/-siBRM. Cells were then left untreated or exposed to IFNg for 6 hours. Total RNA was collected and analyzed with Illumina arrays. SW13 cells were transfected with siSUZ12+/-siBRM or control siRNA+/-siBRM. Cells were left untreated or exposed to IFNg for 6 hours.

2015-05-01 | E-GEOD-67628 | biostudies-arrayexpress

The effect of SUZ12 knockdown on the responsivness of IFNg Stimulated Genes

2015-05-01 | GSE67628 | GEO

Human neutrophils stimulated with IFNg.

Project description:Studying the effect of Th1 cytokine IFNg on gene expression of human neutrophils by comparing gene expression of neutrophiles isolated from the blood of 3 healthy donors and stimulated with IFNg (10ng/ml) or left unstimulated.

2023-03-28 | GSE135425 | GEO

Gene expression in anti-IgM IFNg treated B cells

Project description:RNAseq data of human naive B cells untreated or stimulated with anti-IgM and IFNg

2021-08-11 | GSE181739 | GEO

IFNg+ vs IFNg- Treg

Project description:Gene expression studies comparing IFNg+ Tregs versus IFNg- Tregs from human peripheral blood Ex vivo sorted Tregs (CD25highCD127neg) were stimulated for 4 hours and IFNg-secreting cells were detected by a IFNg-capture kit. The samples were resorted based on IFNg expression.

2016-07-01 | E-GEOD-71274 | biostudies-arrayexpress

Protein-protein interactions of BRG1 or BRG1-HSA in SW13 cells

Project description:The SWI/SNF complex remodels chromatin in an ATP-dependent manner through the ATPase subunits BRG1 and BRM. Chromatin remodeling alters nucleosome structure to change gene expression, however aberrant remodeling and gene expression can result in cancer. The function and localization on chromatin of the SWI/SNF complex depends on the protein makeup of the complex. Here we report the protein-protein interactions of wild-type BRG1 or mutant BRG1 in which the HSA domain has been deleted (BRG1-HSA). We demonstrate the interaction of BRG1 with most SWI/SNF complex members and a failure of a number of these members to interact with BRG1-HSA. These results demonstrate that the HSA domain of BRG1 is a critical interaction platform for the correct formation of SWI/SNF remodeling complexes.

2023-02-15 | PXD029647 | Pride

Identification of IFNg-regulated, IRF1-dependent genes in Shigella flexneri-infected mouse embryonic fibroblasts (MEFs)

Project description:This experiment was designed to identify IFNg-regulated, IRF1-dependent genes during infection with the intracellular pathogen Shigella flexneri. WT and Irf1-/- MEFs were stimulated for 18 hours with IFNg or left unstimulated; all of the cells were subsequently infected for 6 hours with S. flexneri prior to harvest of total RNA.

2011-09-01 | E-MTAB-713 | biostudies-arrayexpress

IFNg+ vs IFNg- Treg

Project description:Gene expression studies comparing IFNg+ Tregs versus IFNg- Tregs from human peripheral blood

2016-07-01 | GSE71274 | GEO

Comparison of BRG1 reexpression, TSA treatment and 5dAzaC treatment on gene expression in human NCI-H522 NSCLC cells

Project description:Transcription was assessed in the human H522 NSCLC cell line after reexpression of BRG1, one of the mutually exclusive subunits of the SWI/SNF chromatin remodeling complex, by adenovirus infection, after treatment with 5 micromolar 5-deAzacytidine or after treatment with 100nM Trichostatin A. Control treatments included infection with adenovirus expressing GFP and treatment with DMSO4 (vehicle control). The goal of the experiment was to identify target genes of the SWI/SNF complex and compart them to changes induced by DNA methylation and histone acetylation modifiers. One biological replicate of each treatment; 4 technical replicates of each treatment.

2014-01-13 | E-GEOD-54033 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data