Gene expression in CD30+ L540 cell line induced by different anti-CD30 antibodies that bind to different epitopes

ABSTRACT: CD30 receptor (TNFRSF8) is highly expressed in some types of lymphoma. Therefore, CD30 is successfully used as a target for antibody-drug conjugate to treat CD30+ lymphoma. In this study, we compared gene expression profiles induced in CD30+ L540 cell line by treating CD30 natural ligand or anti-CD30 antibodies against different epitopes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE67794 | GEO | 2025/08/10

REPOSITORIES: GEO