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Investigating GPR34 expression regulation using whole transcriptome sequencing of spleens and dendritic cells from wildtype and GPR34 knockout mice

ABSTRACT: Naive spleens as well as naive and LPS-treated dendritic cells from wildtype and GPR34-/- mice were sequenced to integrate expression profiles with protein interaction networks and find functional modules that are affected by GPR34

ORGANISM(S): Mus musculus

PROVIDER: GSE68155 | GEO | 2016/03/02

SECONDARY ACCESSION(S): PRJNA281932

REPOSITORIES: GEO

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Investigating GPR34 expression regulation using whole transcriptome sequencing of spleens and dendritic cells from wildtype and GPR34 knockout mice

Project description:Naive spleens as well as naive and LPS-treated dendritic cells from wildtype and GPR34-/- mice were sequenced to integrate expression profiles with protein interaction networks and find functional modules that are affected by GPR34 Expression profiles of dendritic cells and whole spleens were generated using Illumina HiSeq 2500/ Illumina HiScan

2016-03-02 | E-GEOD-68155 | biostudies-arrayexpress

GPR34 regulation of disease-associated microglial states in mice

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GPR34 senses myelin debris to promote neuroinflammation and pathology

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GPR34 senses demyelination to promote neuroinflammation and cognition impairment in Alzheimer's disease

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