Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Systems analysis of uterine microenvironment 4, 6, 8, 10, 11 or 12 days after fertilization

ABSTRACT: Analysis of uterine microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchestrated the immune reponse triggered in presence of embryo

ORGANISM(S): Mus musculus

PROVIDER: GSE68433 | GEO | 2015/12/10

SECONDARY ACCESSION(S): PRJNA282756

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Systems analysis of uterine microenvironment 4, 6, 8, 10, 11 or 12 days after fertilization

Project description:Analysis of uterine microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchestrated the immune reponse triggered in presence of embryo Total RNA obtained from uterine microenvironment tissues (4, 6, 8, 10, 11 or 12 days after fertilization) compared to control tissues (uterus from non pregnant mice).

2015-12-10 | E-GEOD-68433 | biostudies-arrayexpress

Systems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization

2015-12-10 | GSE68432 | GEO

Systems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization

Project description:Analysis of uterine microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchestrated the immune reponse triggered in presence of embryo. Total RNA obtained from uterine microenvironment tissues of Treg depleted pregnant mice (12 days after fertilization) compared to control tissues (uterus from PBS treated pregnant mice).

2015-12-10 | E-GEOD-68432 | biostudies-arrayexpress

Systems analysis of B16 tumor microenvironment 4 or 14 days after tumor inoculation

Project description:Analysis of B16 tumor microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchastrated the immune reponse triggered in presence of tumors

2015-12-10 | GSE68434 | GEO

Systems analysis of B16-WT, B16-shTGFb and B16-shVEGF tumor microenvironment 4 or 14 days after tumor inoculation

2016-09-01 | GSE73384 | GEO

Systems analysis of B16-WT, B16-shTGFb and B16-shVEGF tumor microenvironment 4 or 14 days after tumor inoculation

Project description:Analysis of B16 tumor microenvironments at gene expression level. The hypothesis tested in the present study was that Tregs orchastrated the immune reponse triggered in presence of tumors Total RNA obtained from tumor microenvironment tissues (at Day 4 and Day 14 after tumor inoculation) compared to control tissues.

2016-09-01 | E-GEOD-73384 | biostudies-arrayexpress

Regulatory T cell adoptive transfer alters uterine macrophage populations, increasing a novel MHC-II-low macrophage associated with healthy pregnancy.

Project description:To investigate local immune mechanisms of intrauterine fetal demise (IUFD), we used the CBA mouse strain, which naturally has mid-late gestation fetal loss. We performed a Treg adoptive transfer and interrogated both pregnancy outcomes and the impact of systemic maternal Tregs on mucosal immune populations at the maternal-fetal interface. Treg transfer prevented fetal loss and increased an MHC-IIlow population of uterine macrophages. Single-cell RNA-sequencing was utilized to precisely evaluate the impact of systemic Tregs on uterine myeloid populations. A population of C1q+, Trem2+, MHC-IIlow uterine macrophages were increased in Treg-recipient mice. The transcriptional signature of this novel uterine macrophage subtype is enriched in multiple studies of human healthy decidual macrophages, suggesting a conserved role for these macrophages in preventing fetal loss.

2023-10-09 | GSE244616 | GEO

Transcription profiling of mouse uterine horns from Hoxa-10+/+ and Hoxa-10-/- littermates

Project description:Female mice used were SvJ/129, 10-16 weeks of age; Hoxa-10+/+ and Hoxa-10-/- littermates were used in parallel experiments. 14 days after ovariectomy, mice were injected subcutaneously with progesterone dissolved in sesame oil (Sigma; 0.2mg/0.1mL/mouse), followed by sacrifice and removal of uterine horns at 6 hours after injection. 8 uterine horns from 4 mice were pooled to form one sample. Total RNA preparation, cRNA labeling and hybridization were performed according to recommendations by Affymetrix. The 6 samples were obtained and processed in two batches: (1: GSM3047 and GSM3041), and (2: GSM3048, GSM3049, GSM3042, and GSM3043).

2007-10-06 | E-GEOD-108 | biostudies-arrayexpress

Uterine microbiota

Project description:Uterine microbiota Metagenome

| PRJNA480713 | ENA

Uterine extracellular vesicles in the mare.

Project description:The protein cargos of uterine extracellular vesicles isolated from uterine lavages, collected from pregnant mares (P; day 10, 11, 12 and 13 after insemination) and cyclic control mares (C; day 10 and 13 after insemination), was analyzed.

2022-10-15 | PXD032405 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data