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Expression data of sandwich cultured primary rat hepatocytes incubated to piperazine designer drugs

ABSTRACT: The piperazine derivatives most frequently consumed for recreational purposes are 1-benzylpiperazine (BZP), 1-(3,4-methylenedioxybenzyl)piperazine (MDBP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP), and 1-(4-methoxyphenyl)piperazine (MeOPP). Currently it is unclear whether piperazine designer drugs induce mechanisms of hepatotoxicity and, if so, whether they act by a common mechanism. We performed a gene array study with rat hepatocytes incubated with the four designer drugs for 24 h in order to detail the global programme of gene expression

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE68785 | GEO | 2015/05/13

SECONDARY ACCESSION(S): PRJNA283856

REPOSITORIES: GEO

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Expression data of sandwich cultured primary rat hepatocytes incubated to piperazine designer drugs

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