MLL1 and MLL fusion proteins play distinct roles in regulating MLLleukemic transcription program [ChIP-Seq]

ABSTRACT: This study describes the epigenetic profiling change of 1.) Mll1, WDR5 and H3K4me2 in mouse MAF9 leukemia cells treated with or without MM401; 2.) WDR5 and H3K4me2 epigenetic profiling in MLL1 flox/flox, ER-Cre+/- cells with knocking out MLL1 by 4OHT or not.

ORGANISM(S): Mus musculus

PROVIDER: GSE68821 | GEO | 2016/05/12

SECONDARY ACCESSION(S): PRJNA283891

REPOSITORIES: GEO