Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from high-fat diet feeded WT and LIGHT Tg mice

ABSTRACT: effect of over-expression LIGHT on T cells for the liver gene expression We used microarrays to detail the global programme of gene expression underlying WT and LIGHT Tg liver Keywords: genetic difference

ORGANISM(S): Mus musculus

PROVIDER: GSE6903 | GEO | 2007/08/03

SECONDARY ACCESSION(S): PRJNA98151

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling of mouse liver isolated from high-fat diet feeded WT and LIGHT Tg mice

Project description:effect of over-expression LIGHT on T cells for the liver gene expression; We used microarrays to detail the global programme of gene expression underlying WT and LIGHT Tg liver Experiment Overall Design: mice were selected at 4-8 wks old after 2 weeks HFD feeding for RNA extraction and hybridization on Affymetrix microarrays. The total liver were used.

2008-06-15 | E-GEOD-6903 | biostudies-arrayexpress

Expression profiles of zebrafish transgenic line Tg(fabp10a:def)-I

2013-02-28 | GSE41059 | GEO

Expression profiles of zebrafish transgenic line Tg(fabp10a:def)-I

Project description:We previously reported that Def (Digestive-organ expansion factor) was a pan-endodermal enriched factor that is essential for the growth of digestive organs in zebrafish using a def mutant line hi429 as model (Chen et al., 2005). To further elucidate Def function, we generated a Def over-expressed zebrafish line, namely Tg (fabp10a:def)-I, in which def expression was under the control of a liver-specific promoter fabp10a. We used microarrays to detail the global programme of gene expression in Tg (fabp10a:def)-I transgenic line compared with wild type zebrafish control, and identified distinct classes of differently regulated genes in Tg (fabp10a:def)-I line. Total RNA from the adult livers of three independent batches of 3-month-old Tg(fabp10a:def)-I and wild type (AB strain) male fish was extracted using TRIzol (Invitrogen), each batch with the liver samples from three fish mixed together. The samples were subjected to microarray hybridization and the data were generated for further analysis.

2013-02-28 | E-GEOD-41059 | biostudies-arrayexpress

Expression data from liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

Project description:We used microarrays to detail the global programme of gene expression in the liver of Pemt-/- and Pemt+/+ under HFHS diets.

2015-04-14 | GSE67792 | GEO

Expression data from liver samples of Pemt-/- and Pemt+/+ mice under high fat-high-sucrose (HFHS) diet

Project description:We used microarrays to detail the global programme of gene expression in the liver of Pemt-/- and Pemt+/+ under HFHS diets. Liver sample of Pemt-/- and Pemt+/+ mice under HFHS for 1, 2, 3, 4 weeks were used for RNA extraction and hybridization on Affymetrix microarrays. Genes in liver of Pemt-/- mice, successively suppressed compared with Pemt+/+ mice, were obtained.

2015-04-14 | E-GEOD-67792 | biostudies-arrayexpress

RNAseq of livers from High Fat Diet and Low Fat Diet fed mice, sampled every 4 hours over one full cycle, living in either short light, long light, or equal light photoperiods

Project description:RNAseq of livers from High Fat Diet and Low Fat Diet fed mice, sampled every 4 hours over one full cycle, living in either short light, long light, or equal light photoperiods

2023-09-09 | GSE201584 | GEO

Expression data from liver of Cyclocarya paliurus triterpenic acids treated high-fat-diet-induced mice

Project description:Diverse targets and metabolic pathways are involved in NAFLD, which accounts for the difficulties in achieving the predominant therapeutic effects in clinical practice. Lipid accumulation is the ‘first hit’ in the development of NAFLD in liver, the dysregulation of lipid disposal can lead to hepatic steatosis. Oxidative stress is the ‘second hit’ in the pathogenesis of NAFLD. CP triterpenic acid (CPT) had an ameliorative effect on metabolic diseases, such as non-alcoholic hepatic steatosis. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process.

2020-01-01 | GSE125045 | GEO

Expression data from hypothalamic samples of WT mice fed normal diet vs high fat diet

Project description:The consumption of a 60% high fat diet leads to increased body weight and the development of the metabolic syndrome. We analyzed hypothalamic samples of WT mice as it has been previously shown that the hypothalamus plays a crucial role in the regulation of energy homeostasis. We used microarrays to detail the global programme of gene expression affected by the consumption of a high fat diet specifically in the hypothalamus of WT mice.

2019-05-01 | GSE127056 | GEO

Expression data from Arabidopsis seedlings heat-stressed in light environment

Project description:Plants transcriptome react to environment temperture changes profoundly. In Arabidopsis seedlings, genes response to temperature fluctuations to adopt the ever-changing ambient envrionment. We used microarrays to detail the global programme of gene expression underlying heat stress response progress in Arabidopsis. Ten-day-old Arabidopsis seedlings were selected for RNA extraction and hybridization on Affymetrix microarrays. We sought to explore the heat stress response in transcriptome, thus we treat the plants with heat stress. While in order to identify the interaction between light and temperature signaling pathways in plant , we treat Arabidopsis with heat stress under both light and dark conditions. To that end, our plant tissues are grouped as: HS-LIGHT, HS-DARK,CONTROL-LIGHT,CONTROL-DARK.

2014-06-19 | E-GEOD-58616 | biostudies-arrayexpress

Liver mRNA expression in high fat diet fed mice with hepatic specific Slug knockout

Project description:Liver steatosis is a driving force for nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease, insulin resistance, and type 2 diabetes. Slug (also called Snai2 or Snail2) is a transcriptional regulator that may play a critical role in the regulation of liver function. To prove that, we used microarrays to detail the hepatic Slug regulated gene expression underlying liver steatosis and identified distinct pathways controlled by Slug during this process.

2020-02-18 | GSE145404 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data