An Nfic-Hedgehog Signaling Cascade Regulates Tooth Root Development

ABSTRACT: This study aimed to perform transcriptome profiling of Nfic-/- and corresponding control tooth germ at root initiation stage to identify differentially expressed for key regulators of root development. Coordination between the Hertwig’s Epithelial Root Sheath (HERS) and apical papilla (AP) is crucial for proper root development process. The Hedgehog (Hh) signaling pathway and Nfic are both involved in tooth root development.

ORGANISM(S): Mus musculus

PROVIDER: GSE69054 | GEO | 2017/08/29

SECONDARY ACCESSION(S): PRJNA284406

REPOSITORIES: GEO