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Gene expression profiling of E13.5 Eda null embryonic mammary buds

ABSTRACT: TNF ligand ectodysplasin-A1 contributes to embryonic mammary gland development. We searched for target genes of the Eda pathway using profiling of genes differentially expressed in Eda-null mammary buds after a short exposure to recombinant Fc-Eda-A1 protein.

ORGANISM(S): Mus musculus

PROVIDER: GSE69781 | GEO | 2015/11/01

SECONDARY ACCESSION(S): PRJNA286767

REPOSITORIES: GEO

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Gene expression profiling of E13.5 Eda null embryonic mammary buds

Project description:TNF ligand ectodysplasin-A1 contributes to embryonic mammary gland development. We searched for target genes of the Eda pathway using profiling of genes differentially expressed in Eda-null mammary buds after a short exposure to recombinant Fc-Eda-A1 protein. Microdissected E13.5 Eda-/- epithelial mammary buds from 5-6 embryos were pooled together. Other half of an embryo was used as a control and the other half as a treated sample. Littermates from 3 litters of B6CBA background were used for the analysis. Array and data analysis were performed in the Biomedicum Functional Genomics Unit (University of Helsinki, Finland).

2015-11-01 | E-GEOD-69781 | biostudies-arrayexpress

Eda targets

Project description:Pools of 3 E14 eda null half skin pairs were cultured for 90 minutes or 4 hours in hanging drops of medium containing 2ug/mL of Fc-Eda-A1 (treated halves) or the equivalent amount of solvent (control halves). Biological triplicates for each condition were performed.

2011-12-24 | E-MEXP-3341 | biostudies-arrayexpress

Eda

Project description:Rattus norvegicus Eda, ectodysplasin-A [Source:RGD Symbol;Acc:1563178], is expressed in 6 baseline experiment(s);

| ENSRNOG00000032208 | ExpressionAtlas

EDA

Project description:Monodelphis domestica EDA, ectodysplasin A [Source:NCBI gene;Acc:100014487], is expressed in 2 baseline experiment(s);

| ENSMODG00000004650 | ExpressionAtlas

Eda

Project description:Rattus norvegicus Eda, ectodysplasin-A [Source:RGD Symbol;Acc:1563178], is differentially expressed in 2 experiment(s);

| ENSRNOG00000032208 | ExpressionAtlas

EDA

Project description:Macaca mulatta EDA, ectodysplasin A [Source:VGNC Symbol;Acc:VGNC:72153], is expressed in 2 baseline experiment(s);

| ENSMMUG00000017753 | ExpressionAtlas

EDA

Project description:Oryctolagus cuniculus EDA, ectodysplasin A [Source:HGNC Symbol;Acc:HGNC:3157], is expressed in 1 baseline experiment(s);

| ENSOCUG00000015594 | ExpressionAtlas

EDA

Project description:Homo sapiens EDA, ectodysplasin A [Source:HGNC Symbol;Acc:HGNC:3157], is expressed in 35 baseline experiment(s);

| ENSG00000158813 | ExpressionAtlas

EDA

Project description:Sus scrofa EDA, ectodysplasin A [Source:VGNC Symbol;Acc:VGNC:87540], is differentially expressed in 2 experiment(s);

| ENSSSCG00000021647 | ExpressionAtlas

EDA

Project description:Sus scrofa EDA, ectodysplasin A [Source:VGNC Symbol;Acc:VGNC:87540], is expressed in 1 baseline experiment(s);

| ENSSSCG00000021647 | ExpressionAtlas

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