Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration

ABSTRACT: Gene expression analysis showed that LncPHx2 depletion resulted in upregulation of mRNAs encoding proteins known to promote cell proliferation, including MCM components, DNA polymerases, histone proteins, and transcription factors

ORGANISM(S): Mus musculus

PROVIDER: GSE70283 | GEO | 2015/06/26

SECONDARY ACCESSION(S): PRJNA288153

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration

Project description:Gene expression analysis showed that LncPHx2 depletion resulted in upregulation of mRNAs encoding proteins known to promote cell proliferation, including MCM components, DNA polymerases, histone proteins, and transcription factors RNA-seq analysis was performed on livers of mice subjected to PHx or to sham surgery after treatment with LncPHx2_ASO1 or with PBS. Gene expression profiling was done at 48 hours post-surgery

2015-06-26 | E-GEOD-70283 | biostudies-arrayexpress

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.

Project description: Not available

| S-EPMC4514479 | biostudies-literature

Partial hepatectomy?induced upregulation of SNHG12 promotes hepatocyte proliferation and liver regeneration.

Project description: Not available

| S-EPMC7003022 | biostudies-literature

Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-06-26 | E-GEOD-70343 | biostudies-arrayexpress

Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration

Project description:This SuperSeries is composed of the SubSeries listed below.

2015-06-26 | GSE70343 | GEO

Hepatocyte Peroxisome Proliferator-Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice.

Project description: Not available

| S-EPMC6593252 | biostudies-literature

Expression data from rat hepatocyte during liver regeneration after partial hepatectomy

Project description:The recovery of liver mass is mainly mediated by proliferation and enlargement of hepatocytes after partial hepatectomy. Studying the gene expression profiles of hepatocytes after partial hepatectomy will be helpful in exploring the mechanism of liver regeneration. We used microarrays to further highlight the regulatory role of hepatocyte in liver regeneration at gene transcription level. Rat liver regeneration after partial hepatectomy (PH) is a good model to study the regulation of cell proliferation. We isolated hepatocytes from regenerating liver at 9 time points (2, 6, 12,24, 30, 36, 72, 120, and 168h) after PH and measured gene expression profiles of hepatocytes from 2h to 168h with rat Genome 230 2.0 gene chip. Each sample corresponding to one time point was hybridized onto one array. The experiment was repeated 3 times for each time point. In total, 10 time points were measured and 0h was used control group. After careful quality control analyses of each chip, Affymetrix GCOS 2.0 software was used to analyze the data. The relevance of gene expression profiles and biological processes was analyzed by bioinformatics and systems biology.

2014-02-28 | E-GEOD-55434 | biostudies-arrayexpress

Expression data from rat hepatocyte during liver regeneration after partial hepatectomy

2014-02-28 | GSE55434 | GEO

Impaired liver regeneration after hepatectomy and bleeding is associated with a shift from hepatocyte proliferation to hypertrophy.

Project description: Not available

| S-EPMC5690394 | biostudies-literature

Endothelial nitric oxide synthase is a key mediator of hepatocyte proliferation in response to partial hepatectomy in mice.

Project description: Not available

| S-EPMC3579770 | biostudies-literature