Genome-wide epigenetic cross-talk between DNA methylation and H3K27me3 in zebrafish embryos

ABSTRACT: DNA methylation and histone modifications are epigenetic marks implicated in the complex regulation of vertebrate embryogenesis. The cross-talk between DNA methylation and Polycomb-dependent H3K27me3 histone mark has been reported in a number of organisms and both marks are known to be required for proper developmental progression. Here we provide genome-wide DNA methylation (MethylCap-seq) and H3K27me3 (ChIP-seq) maps for three stages (dome, 24hpf and 48hpf) of zebrafish (Danio rerio) embryogenesis, as well as all analytical and methodological details associated with the generation of this dataset.

ORGANISM(S): Danio rerio

PROVIDER: GSE70847 | GEO | 2015/07/22

SECONDARY ACCESSION(S): PRJNA289683

REPOSITORIES: GEO