Neoadjuvant chemotherapy modulates T cell responses in high-grade serous ovarian cancer metastases

ABSTRACT: Our data suggest that neoadjuvant chemotherapy enhances anti-cancer responses of T cells in peritoneal metastases of patients with high-grade serous ovarian cancer but does not decrease levels of immune checkpoint molecules, providing a rationale for sequential chemo-immunotherapy.

ORGANISM(S): Homo sapiens

PROVIDER: GSE71340 | GEO | 2016/07/27

SECONDARY ACCESSION(S): PRJNA290924

REPOSITORIES: GEO