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Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet

ABSTRACT: Here we report the genome-wide DNA methylation analyses by MeDIP-seq, performed on epididymal fat of mice fed either high-fat or regular chow diet.

ORGANISM(S): Mus musculus

PROVIDER: GSE71476 | GEO | 2015/10/01

SECONDARY ACCESSION(S): PRJNA291350

REPOSITORIES: GEO

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Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion - 16S

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2022-05-06 | E-MTAB-11551 | biostudies-arrayexpress

Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion - primary L cells

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Gene expression changes in aortas of mice on high fat versus regular chow diet.

Project description:To determine effects of hyperglycemia and insulin resistance on arterial wall biology, gene expression profiles were generated using aortas from mice on high fat (35% fat) diet and their respective non diabetic regular chow fed controls. Keywords: Chip Experiment was done in triplicate with three independent pools from test mice on high fat diet and control mice on regular chow diet. For RNA isolation aortas were striped of adventitia and periaortic fat. RNA from three aortas was pooled for the synthesis of probe for affymetrix array analysis.

2011-12-23 | E-GEOD-6735 | biostudies-arrayexpress

Proteomics of liver from mice fed high fat diet (HFD) or regular chow diet

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2021-10-27 | PXD029280 | Pride

Proteomics analysis of insulin sensitive tissues in high fat diet fed mice

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2022-01-26 | PXD021046 | Pride

Gene expression changes in aortas of mice on high fat versus regular chow diet.

2011-12-23 | GSE6735 | GEO

Estrogen signaling and fatty liver disease

Project description:We propose comparing liver gene expression of WT and female ERKO mice early in the high-fat feeding period to animals fed a regular chow diet. Analyzing liver tissue before the fatty liver disease phenotype becomes severe will allow identification of target genes which may be causal. Comparison of regular chow fed WT animals to high fat fed WT animals will allow for identification of hepatic genes up-regulated in response to high fat feeding. Comparison of regular chow fed WT animals to regular chow fed ERKO animals will help clarify hepatic gene expression patterns that may be implicated in increased susceptibility to weight gain and glucose intolerance. Comparison of high fat fed WT animals to high fat fed ERKO animals will provide insight into genes that could be implicated in leading to increased fat accumulation in the liver over time during high fat feeding. Finally, comparison of regular chow fed ERKO animals to high fat fed ERKO animals will help identify genes that may be contributing to increased liver fat accumulation in response to high fat feeding in these animals.

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Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K27ac and H3K9me3 in liver tissues from high fat and regular chow diet mice.

Project description:Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K27ac and H3K9me3 in liver tissues from high fat and regular chow diet mice.

2023-05-01 | GSE226171 | GEO

Differential expression of genes in pancreatic islet of C57Bl/6J on high fat diet

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2011-11-20 | GSE23325 | GEO

RNAseq to profile transcriptomes in adipose tissue macrophages (ATMs) from TKO(mir-106a~363-/- mir-106b~25-/- mir-17~92flox/flox Lyz2-Cre) and WT(Lyz2-Cre) mice fed with regular chow diet or high fat diet.

Project description:We performed the transcriptomic analysis of RNA-seq of ATMs generated from WT and TKO mice fed with regular chow diet or high fat diet.

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