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Histone deacetylase inhibitor enhanced salinity stress response

ABSTRACT: To identify salt-resistant related genes by histone deacetylase inhibitor Ky-2, expression profiles between plants treated with or without Ky-2 under salt stress were analyzed using the custom microarray (GPL20781).

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE71855 | GEO | 2015/08/08

SECONDARY ACCESSION(S): PRJNA292335

REPOSITORIES: GEO

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Histone deacetylase inhibitor enhanced salinity stress response

Project description:To identify salt-resistant related genes by histone deacetylase inhibitor Ky-2, expression profiles between plants treated with or without Ky-2 under salt stress were analyzed using the custom microarray (GPL20781). Wild-type plants (Arabidopsis thaliana ecotype Columbia) were grown on 1/2 MS 0.1 % Agar medium for four days. Then, the plants were administrated to Ky-2 for 24 hours and then treated 100 mM Nacl for two hours. Expression profiles were analyzed using the custom array (GPL20781).

2015-08-08 | E-GEOD-71855 | biostudies-arrayexpress

FSL0260 enhanced salinity stress response

Project description:To identify salt-resistant related genes by FSL0260, expression profiles between plants treated with or without FSL0260 under salt stress were analyzed using the custom microarray (GPL19830).

2020-05-27 | GSE128820 | GEO

Natolen128 enhanced salinity stress response

Project description:To identify salt-resistant related genes by Natolen128, which identified from ITbM chenical library, expression profiles between plants treated with or without Natolen128 under salt stress were analyzed using the custom microarray (GPL19830).

2021-06-02 | GSE173340 | GEO

Transcriptomic Analysis of Arabidopsis plants treated with Histone Deacetylase inhibitors, Ky-9 and Ky-72

Project description:To analyze the molecular function of HDAC inhibitors in salt stress responses in Arabidopsis, we conducted microarray analysis using 4-day-old plants, which were treated with 1 μM Ky-9 or Ky-72 or water for 24 h, and then treated with or without 100 mM NaCl for 2 h

2018-05-09 | GSE108070 | GEO

The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Alleviates Salinity Stress in Cassava.

Project description: Not available

| S-EPMC5220070 | biostudies-literature

Proteome-wide lysine acetylation profiling to investigate the involvement of histone deacetylase HDA5 in the salt stress response of Arabidopsis leaves

Project description:Post-translational modifications (PTMs) of proteins play important roles in the acclimation of plants to environmental stress. Lysine acetylation is a dynamic and reversible PTM, which can be removed by histone deacetylases. Here we investigated the role of lysine acetylation in the response of Arabidopsis leaves to one week of salt stress. A quantitative mass spectrometry analysis revealed an increase in lysine acetylation of several proteins from cytosol and plastids, which was accompanied by an altered HDAC activity in the salt-treated leaves. While activities of HDA14 and HDA15 were decreased upon salt stress, HDA5 showed a mild and HDA19 a strongly increased activity. Since HDA5 is a cytosolic-nuclear enzyme from the class II histone deacetylase family with yet unknown protein substrates, we performed a lysine acetylome analysis on hda5 mutants and characterized its substrate proteins. Next to histone H2B, the salt stress responsive transcription factor GT2L and the dehydration-related protein ERD7 were identified as HDA5 substrates. In addition, in protein-protein interaction studies HDA18 was discovered, among other interacting proteins, to work in a complex together with HDA5. Altogether this study revealed the substrate proteins of HDA5 and identified new lysine acetylation sites which are hyperacetylated upon salt stress. The identification of the specific histone deacetylase substrate proteins, apart from histones, will be important to unravel the acclimation response of Arabidopsis to salt stress and their role in plant physiology.

2023-03-28 | PXD032867 | JPOST Repository

Transcriptomic Analysis of Arabidopsis plants treated with Histone Deacetylase inhibitors, Ky-9 and Ky-72

Project description:Transcriptomic Analysis of Arabidopsis plants treated with Histone Deacetylase inhibitors, Ky-9 and Ky-72

| PRJNA422397 | ENA

The Histone Deacetylase Rpd3p Coordinates Transient Changes in Genomic Expression in Response to Acute Stress

Project description:To characterize the role of chromatin remodeling proteins in mediating stress-activated expression changes, whole-genome expression was followed in wild-type and mutant cells (including strains lacking the histone deacetylase Rpd3p, associated Rpd3p proteins, and the transcription factors Msn2p and Msn4p) responding to multiple stresses including heat shock, hydrogen peroxide treatment, and salt stress, as well as stress relief. Keywords: Timecourse and single timepoint expression studies of stress response in yeast

2009-05-21 | GSE9108 | GEO

The Histone Deacetylase Rpd3p Coordinates Transient Changes in Genomic Expression in Response to Acute Stress

2009-05-20 | E-GEOD-9108 | biostudies-arrayexpress

The histone deacetylase inhibitor Suberoylanilide Hydroxamic Acid (SAHA) alleviates salinity stress in cassava (Manihot esculenta Crantz)

Project description:To elucidate the molecular mechanism involved in increased tolerance to high-salinity stress by the application of HDAC inhibitor named SAHA

2016-12-01 | GSE84715 | GEO

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