Comparison of human embryonic stem cell (hESC) derived mesenchymal precursor cell populations

ABSTRACT: We have developed efficient protocols for the derivation of mesenchymal precursors from hESCs. While previous protocols were based on mesodermal induction via co-culture of hESCs on OP9 mouse stroma (Barberi et al., PLoS Biology, 2005), our recent work shows the derivation of hESC derived mesenchymal precurors under feeder-free conditions. The data presented here show a large and highly signficant overlap in global gene expression profiles between hESC derived mesenchymal precursors derived under feeder-free conditions with those derived via OP9 co-culure and mesenchymal precurosrs isolated directly from the adult bone marrow. Keywords: cell type comparison

ORGANISM(S): Homo sapiens

PROVIDER: GSE7332 | GEO | 2007/05/17

SECONDARY ACCESSION(S): PRJNA98055

REPOSITORIES: GEO