Genomics

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Expression data from mouse induced Erythroid Progenitor (iEP)-derived colonies, mouse bone marrow and fetal liver BFU-Es and mouse fibroblasts.


ABSTRACT: Forced expression of Gata1, Tal1, Lmo2 and c-Myc reprograms murine adult fibroblasts into erythroid progenitor cells. The resulting cells, called induced erythroid progenitors/precursors (iEPs), resemble bona fide erythroid cells in terms of morphology, colony forming capacity, and gene expression. We used microarrays to characterize the reprogrammed cells (iEP_red and iEP_non-red) at the molecular level and compare their global gene expression profile with bona fide erythroid cells (FL and BM BFU-Es) and starting fibroblasts (Fibs).

ORGANISM(S): Mus musculus

PROVIDER: GSE73344 | GEO | 2016/04/22

SECONDARY ACCESSION(S): PRJNA296758

REPOSITORIES: GEO

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