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MicroRNA expression data from β-hydroxy-β-methylbutyrate (HMB) pre-incubated differentiating equine satellite cells (ESC) exposed to hydrogen peroxide

ABSTRACT: Transcriptional profiling of HMB-treated (24h) differentiating equine satellite cells (3rd day of differentiation) exposed to hydrogen peroxide (1h; last hour of pre-incubation with HMB) compared to control HMB-untreated cells. Goal was to determine the effects of HMB pre-incubation on miRNA expression in equine satellite cells exposed to hydrogen peroxide.

ORGANISM(S): Equus caballus

PROVIDER: GSE73779 | GEO | 2018/04/03

REPOSITORIES: GEO

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Expression data from differentiating equine satellite cells (ESC) culture incubated with HMB and exposed to hydrogen peroxide

Project description:Transcriptional profiling of HMB-treated (24h) differentiating equine satellite cells (3rd day of differentiation) exposed to hydrogen peroxide (1h; last hour of pre-incubation with HMB) compared to control HMB-untreated cells. Goal was to determine the effects of HMB pre-incubation on gene expression in equine satellite cells exposed to hydrogen peroxide.

2018-04-03 | GSE93025 | GEO

Expression data from differentiating primary culture of equine satellite cells (ESC) β-hydroxy-β-methylbutyrate (HMB)

Project description:Transcriptional profiling of β-hydroxy-β-methylbutyrate-treated (24h) differentiating equine satellite cells (3rd day of differentiation) compared to control HMB-untreated cells. Goal was to determine the effects of HMB influence on gene expression in equine satellite cells during in vitro myogenesis

2016-11-23 | GSE74495 | GEO

Gene expression (GE) data from differentiating equine satellite cells (ESC) culture incubated with phytochemical gamma-oryzanol (GO) and exposed to hydrogen peroxide

Project description:Transcriptional profiling of GO-treated (24h) differentiating equine satellite cells (3rd day of differentiation) exposed to hydrogen peroxide (1h; last hour of pre-incubation with GO) compared to control GO-untreated cells. Goal was to determine the effects of GO pre-incubation on gene expression in equine satellite cells exposed to hydrogen peroxide.

2018-12-03 | GSE122098 | GEO

MicroRNA expression data from gamma-oryzanol (GO) pre-incubated differentiating equine satellite cells exposed to hydrogen peroxide

Project description:Transcriptional profiling of GO-treated (24h) differentiating equine satellite cells (3rd day of differentiation) exposed to hydrogen peroxide (1h; last hour of pre-incubation with GO) compared to control GO-untreated cells. Goal was to determine the effects of GO pre-incubation on miRNA expression in equine satellite cells exposed to hydrogen peroxide.

2018-12-03 | GSE122580 | GEO

Equus caballus

Project description:Expression data from differentiating equine satellite cells (ESC) culture incubated with HMB and exposed to hydrogen peroxide

| PRJNA359482 | ENA

Chronic Dosed-Feed Toxicity/Carcinogenicity Study of 2-Hydroxy-4-Methoxybenzophenone (HMB, C10260; CAS No. 131-57-7) in Sprague-Dawley rats (G822872B)

Project description:2-Hydroxy-4-methoxybenzophenone (HMB) is an approved Food and Drug Administration (FDA) over-the-counter Category I product considered to be a deterrent to ultraviolet (UV) radiation-induced skin cancer. HMB is used in pharmaceuticals, plastic products, fabric coatings, finishes, and cosmetics. Exposure to HMB occurs through both occupational and consumer routes. HMB is used in skin moisturizing products and sunscreen lotions. In plastics manufacturing, HMB is used in surface coatings and polymers including ABS resins, cellulosic esters, polyesters, polystyrenes, rubber, flexible and rigid vinyl, and vinylidene chloride. HMB readily penetrates the skin and bioaccumulates in lipid-rich tissues. Uptake from the gastrointestinal tract is rapid. This study will characterize the toxicologic and carcinogenic potential of HMB administered in dosed feed to Sprague-Dawley rats given its potential for widespread human exposure as a broad-spectrum sunscreen.

2022-06-01 | GSE146485 | GEO

Effect of beta-hydroxy-beta-methylbutyrate (HMB) enriched oral nutrition supplement on surgical outcomes and physical performance in colorectal cancer patients: a randomized Controlled Trial

Project description:Interventions: The patient receives standard oral supplement (Ensure),The patient receives beta-hydroxy-beta-methylbutyrate (HMB) enriched oral supplement;Treatment,Treatment;Group 1 ,Group 2 Primary outcome(s): physical performance 1 month Short Physical Performance Battery (SPPB),physical performance 1 month Handgrip strength test ,Bioelectrical Impedance Analysis (BIA) 1 month Bioelectrical Impedance Analysis (BIA)

| 2738383 | ecrin-mdr-crc

Produced β-hydroxybutyrate after β-hydroxy-β-methylbutyrate (HMB) administration may contribute HMB function in mice.

Project description: Not available

| S-EPMC8358161 | biostudies-literature

Modulation of macrophage polarization by HMB [muscle]

Project description:to determine whether hydroxymethyl butyrate alters PDAC response to anti-PD1 therapy, mice bearing PANC02 tumors were treated with anti-PD1 with or without HMB supplementation, gastroc mucsle was isolated from ctrl and HMB groups and analysed by microarray for HMB induced differences in gene expression

2021-12-29 | GSE178476 | GEO

Gene expression data of prostate of PND 30 Sprague-Dawley rats (SD:Hsd) dosed prenatally and lactationally with HMB

Project description:2-hydroxy-4-methoxybenzophenone (HMB) has been reported to have weak estrogenic activity by in vivo and in vitro studies, making it a chemical with potential reproductive concern. To explore if perinatal HMB exposure altered the gene expression profiling in the rat prostate, we analyzed whole genome and mitochondria-related gene expression profiling on the Prostate ontained from Sprague-Dawley rat offspring exposed prenatally and lactationally to varying dose of HMB.

2018-08-31 | GSE111261 | GEO

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