MiRNA gene expression signatures for IhhN protein induced cells

ABSTRACT: Previous studies demonstrated that hererozygous missense mutations in IHH could lead to a decreasing IHH signaling efficacy and cause brachydactyly type A1 (BDA1). For revealing difference of Gli1-mediated downstream regulatory effects between wild type IHH signaling and E95K mutant IHH signaling, we have employed whole genome microarray miRNA expression profiling as a discovery platform to identify miRNAs with the potential to take part in Gli1-mediated cis-regulatory network.

ORGANISM(S): Mus musculus

PROVIDER: GSE74020 | GEO | 2015/10/15

SECONDARY ACCESSION(S): PRJNA298757

REPOSITORIES: GEO