Transcriptomics

Dataset Information

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IFN type I-induced gene expression from brain endothelia


ABSTRACT: Brain endothelial cells are an essential part of the blood-brain-barrier (BBB) and, as such, are exposed to proinflammatory mediators as well as danger signals during infections. They might function as decisive cells mediating RNA virus- and IFN-mediated sickness behavior. To better understand how brain endothelial cells modulate sickness behavior associated with virus-induced IFN release, we challenged endothelia with IFNbeta and investigated the transcription profile after IFNAR1 engagement

ORGANISM(S): Mus musculus

PROVIDER: GSE74061 | GEO | 2016/04/20

SECONDARY ACCESSION(S): PRJNA298890

REPOSITORIES: GEO

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