Genomics

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Reduced insulin production relieves endoplasmic reticulum stress and induces beta-cell proliferation


ABSTRACT: We define the effects of reduced insulin production in beta-cells from tamoxifen-treated Ins1-/-:Ins2f/f:Pdx1CreERT:mTmG mice studied at a time point when insulin production was reduced by ~50%.

ORGANISM(S): Mus musculus

PROVIDER: GSE74113 | GEO | 2015/11/16

SECONDARY ACCESSION(S): PRJNA299027

REPOSITORIES: GEO

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