Transcriptomics,Genomics

Dataset Information

48

Muscle Transcriptome Profile of Resistance Exercise is Augmented by Aerobic Exercise


ABSTRACT: 10 male subjects performed ~45 min one-legged cycling and 4 x 7 maximal concentric-eccentric knee extensions for each leg 15 min later. Thus, one limb performed aerobic and resistance exercise (AE+RE), while the opposing leg did resistance exercise only (RE). Biopsies were obtained from m. vastus lateralis of each leg 3 h after the resistance exercise bout. Gene expression analysis was carried out on the Affymetrix HuGene-2.1-st platform. Overall design: Skeletal muscle gene expression after a single bout of one-legged resistance type exercise only or one bout of one-legged resistance type exercise combined with one bout of aerobic exercise

INSTRUMENT(S): [HuGene-2_1-st] Affymetrix Human Gene 2.1 ST Array [transcript (gene) version]

SUBMITTER: Eric Rullman  

PROVIDER: GSE74194 | GEO | 2016-05-24

SECONDARY ACCESSION(S): PRJNA299300

REPOSITORIES: GEO

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Publications

Aerobic exercise augments muscle transcriptome profile of resistance exercise.

Lundberg Tommy R TR   Lundberg Tommy R TR   Fernandez-Gonzalo Rodrigo R   Tesch Per A PA   Rullman Eric E   Gustafsson Thomas T  

American journal of physiology. Regulatory, integrative and comparative physiology 20160413 11


Recent reports suggest that aerobic exercise may boost the hypertrophic response to short-term resistance training. This study explored the effects of an acute aerobic exercise bout on the transcriptional response to subsequent resistance exercise. Ten moderately trained men performed ∼45 min cycling on one leg followed by 4 × 7 maximal knee extensions for each leg, 15 min later. Thus, one limb performed aerobic and resistance exercise (AE + RE) while the opposing leg did resistance exercise onl  ...[more]

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