Comparative gene expression in adult SVZ-neurospheres neuronally differentiated under standard conditions and upon PARP1 inhibition

ABSTRACT: The relevance of DNA-dependent poly-ADP ribose production for neuronal differentiation of adult stem- and progenitor cells from the SVZ was studied. To identify genes whose up- or downregulation during neuronal differentiation requires the activity of poly-ADP-Ribosylase (PARP) 1 or 2, SVZ-derived adult neurosphere cultures were differentiated in the presence or absence of Olaparib.

ORGANISM(S): Mus musculus

PROVIDER: GSE74314 | GEO | 2017/07/17

SECONDARY ACCESSION(S): PRJNA299653

REPOSITORIES: GEO