Genomics

Dataset Information

0

Transcriptome Analysis of Drosophila Mushroom Body Neurons by Cell Type Reveals Memory-Related Changes in Gene Expression


ABSTRACT: We report the application of low cell number sequencing of identifiable Drosophila melanogaster neurons following behavior. We demonstate the feasibility of identifying the transcriptome of 5 Mushroom Body output Neurons and 2 classes of Kenyon Cells. We find these neurons display a diverse repertoire of receptors and signaling transcripts. This information alone seems to be enough to identify each class of neurons in the study. In additional we show that aversive long-term memory induces changes in gene transcript levels in a subset of these neurons. This study provides a framework for identifying neuronal classes in Drosophila melanogaster and gaining insight into the interplay between behavior and gene regulation.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE74989 | GEO | 2016/05/05

SECONDARY ACCESSION(S): PRJNA302146

REPOSITORIES: GEO

Similar Datasets

| E-MEXP-3798 | biostudies-arrayexpress
2018-09-10 | GSE119629 | GEO
| E-GEOD-37027 | biostudies-arrayexpress
| E-GEOD-37032 | biostudies-arrayexpress
| E-GEOD-10014 | biostudies-arrayexpress
2023-03-11 | PXD034563 | Pride
| E-GEOD-31063 | biostudies-arrayexpress
2014-03-25 | GSE28181 | GEO
2008-06-01 | GSE10014 | GEO
| E-GEOD-10012 | biostudies-arrayexpress