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Heterogeneous expression of zinc-finger E-box-binding homeobox 1 plays a pivotal role in metastasis via regulation of miR-200c in epithelial-mesenchymal transition

ABSTRACT: Although epithelial-mesenchymal transition (EMT) has been implicated as the pivotal event in metastasis, there is insufficient evidence related to EMT in clinical settings. Intratumor heterogeneity may lead to underestimation of gene expression representing EMT. In this study, we investigated the expression of EMT-associated genes and microRNAs in primary colorectal cancer while considering intratumor heterogeneity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE75117 | GEO | 2015/12/25

SECONDARY ACCESSION(S): PRJNA302547

REPOSITORIES: GEO

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