Genomics

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Expression data from the brain of Mus musculus upon intrastriatal administration of baculoviral vectors


ABSTRACT: Recombinant insect baculoviral vectors (BV) efficiently transduce several types of cells in the brain and can possibly be used for gene therapy for brain disorders. To verify the suitability of using these viral vectors to develop gene therapy strategies in the brain, and to evaluate our method of virus purification, we evaluated immune reactions upon acute administration of BV that were purified by ion-exchange membrane chromatography with high-speed centrifugation or high-speed centrifugation alone into the mouse brain using microarray global gene expression profiling.

ORGANISM(S): Mus musculus

PROVIDER: GSE75265 | GEO | 2015/11/21

SECONDARY ACCESSION(S): PRJNA302922

REPOSITORIES: GEO

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