Transcriptomics

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31

Gene Expression Patterns Involved in the Malignant Transformation and Progression of Metastatic Melanoma


ABSTRACT: Metastatic melanoma is a deadly disease while non-metastatic melanoma and other cutaneous tumor types are usually cured with surgical removal of the primary tumors. This study evaluated gene expresion to determine if gene expression differences existed which would allow one to identify the metastatic tumors based on the expression of specific genes. Keywords: multiple tissue comparison Overall design: Tumor samples were collected from patients with various cutaneous tumors, flash frozen, and then processed for gene exprression analysis using microarrays. The pool of tissues includes enough metastatic samples and non-metastatic samples to identify a gene expression signature associated with the outgrowth of the metastatic tumor.

REANALYSED by: GSE119128

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: Sean Yoder   

PROVIDER: GSE7553 | GEO | 2008-05-28

SECONDARY ACCESSION(S): PRJNA100369

REPOSITORIES: GEO

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