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Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers

ABSTRACT: We examined the transcriptional chagnes modulated by ECBI-11 by perfroming global transcriptome analysis. ZR75 cells were treated with either control or ECBI-11 in the presence of E2 for 48 h and the isolated RNA was utilized for RNA-seq analysis. Our results demonstrated that ECBI modulated several genes that are involved in cell cycle, breast cancer signaling, estrogen signaling and apoptosis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE75664 | GEO | 2017/08/18

SECONDARY ACCESSION(S): PRJNA305002

REPOSITORIES: GEO

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