Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Recurrent TRIO fusion in non-translocation-related sarcomas

ABSTRACT: We used NGS on a cohort of complex genetics sarcomas to study their transcriptomes (RNA-seq technology), looking for recurrent and specific gene fusions. We identified multiple TRIO fusions with different partners in our cohort. No TRIO fusions were reported in negative-control cells (normal tissues) and in simple genetics sarcomas.

ORGANISM(S): Homo sapiens

PROVIDER: GSE75885 | GEO | 2017/03/07

SECONDARY ACCESSION(S): PRJNA305611

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Molecular Genetics of Histiocytic Sarcomas

Project description:Molecular Genetics of Histiocytic Sarcomas

| PRJNA507681 | ENA

Molecular Genetics of Histiocytic Sarcomas

Project description:Molecular Genetics of Histiocytic Sarcomas

| PRJNA507682 | ENA

Genomic comparison of post-radiation versus sporadic sarcomas

Project description:Post-radiation sarcomas are rare secondary cancers arising from radiation therapies. To date, few genetic specificities have been described for such malignancies and the oncogenesis of sarcomas with complex genetics (both sporadic and post-radiation) remains largely misunderstood. We performed genomic analyses on both sporadic and post-radiation sarcomas to study their copy-number alterations. This analysis is described in Lesluyes et al. 2019 (PMID: 31243333).

2020-07-17 | GSE154591 | GEO

Angelman syndrome trio

Project description:Exome sequencing Angelman trio

| PRJEB41088 | ENA

20 human soft-tissue sarcomas (TMT)

Project description:SCX fractiond, TMT labeled pleomorphic soft-tissue sarcomas. 32 raw files (8x4) plus 8 pools (also TMT labeled) corresponding to each SCX fraction are submitted. The latter were used to propagate identifications across the runs.

2020-01-27 | PXD000617 | Pride

Trio haploinsufficiency causes neurodevelopmental disease-associated deficits

Project description:TMT 11plex-based proteomic and phosphoproteomic analysis of wild type, NEX-Trio+/- and NEX-Trio-/- mouse cortex sections.

2019-01-31 | MSV000083386 | MassIVE

The Proteomic Landscape of Soft Tissue Sarcomas

Project description:Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of formalin-fixed paraffin embedded tumour specimens from 321 STS patients representing 11 histological subtypes.

2023-05-09 | PXD036226 | Pride

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Project description:RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well sunitinib works in treating patients with metastatic, locally advanced, or locally recurrent sarcomas.

| 2040104 | ecrin-mdr-crc

WT1 Trio Peptide-vaccine for Rare Cancers

Project description:Interventions: A patient is vaccinated with Montanide ISA51-adjuvanted WT1 Trio cancer vaccine consisting of two WT1 CTL peptides (WT1-126 and WT1-235) and one WT1 HTL peptide (WT1-332) (2mg each) seven times at the interval of two weeks. Primary outcome(s): Induction of WT1-specific immune responses assessed by WT1-related tests such as WT1-DTH skin reaction and serum levels of WT1 peptide IgG autoantibody at 1M, 2M, and 3M of WT1 Trio vaccine. Study Design: Single arm Non-randomized

| 2638832 | ecrin-mdr-crc