MicroRNA sequencing in rat cardiac fibroblasts and fibroblast-derived exosomes

ABSTRACT: We found that cardiac fibroblasts produce and secrete exosomes. miRNA profiling and TaqMan qRT-PCR experiments identified miR-21 expression to be higher in cardiac fibroblasts compared to those of miR-21*, whereas in exosomes miR-21* expression was higher compared to miR-21. The purpose of the study was to validate these findings by miRNA sequencing in cardiac fibroblasts and fibroblasts-derived exosomes.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE76175 | GEO | 2015/12/19

SECONDARY ACCESSION(S): PRJNA306519

REPOSITORIES: GEO