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Recurrent rearrangements of the Myb/SANT-like DNA-binding domain containing 3 gene (MSANTD3) in salivary gland acinic cell carcinoma

ABSTRACT: By transcriptome (RNAseq) analysis of 3 human acinic cell carcimoma (AcCC) cases, we discovered two novel gene fusions, and further validated recurrent rearrangement of the MSANTD3 gene. By RNAseq of engineered MSANTD3 overexpression in rat salivary epithelial cells (compared to vector control), we identifed elevated expression of genes involved in protein synthesis.

OTHER RELATED OMICS DATASETS IN: PRJNA307084

ORGANISM(S): Rattus norvegicus Homo sapiens

PROVIDER: GSE76354 | GEO | 2017/02/07

SECONDARY ACCESSION(S): PRJNA307084

REPOSITORIES: GEO

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