Genomics

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KSHV miRNA transfection and inhibition


ABSTRACT: Transcriptional profiling of BJAB cells transfected with KSHV miRNAs and BCBL cells treated with KSHV miRNA inhibitors. To identify host RNA targets of KSHV miRNAs, we took advantage of the observation that RNAs targeted by miRNAs often display small reductions in their steady-state levels, perhaps as a result of their impaired translation. Accordingly, we examined cellular transcript accumulation by array-based expression profiling under four sets of conditions in which KSHV miRNAs were expressed or inhibited.

ORGANISM(S): Homo sapiens

PROVIDER: GSE76472 | GEO | 2017/01/31

SECONDARY ACCESSION(S): PRJNA307557

REPOSITORIES: GEO

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