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Chemical inhibitors of the Mycobacterium tuberculosis DosRST two-component regulatory system

ABSTRACT: The purpose of this study was to discover and characterize small molecule inhibitors of the M. tuberculosis DosRST two-component regulatory pathway. The impact of three novel DosRST regulon inhibitors on gene expression was studied in wild type M. tuberculosis and a DosRS mutant strain.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE76566 | GEO | 2016/12/19

SECONDARY ACCESSION(S): PRJNA307990

REPOSITORIES: GEO

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