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MicroRNA expression levels during the pseudoglandular to canalicular phase transition of fetal lung development

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Homo sapiens

PROVIDER: GSE76921 | GEO | 2016/02/04

SECONDARY ACCESSION(S): PRJNA308935

REPOSITORIES: GEO

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microRNA expression levels during the pseudoglandular to canalicular phase transition of fetal lung development

Project description:microRNA expression levels during the pseudoglandular to canalicular phase transition of fetal lung development

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Project description:Our study demonstrates differential expression of numerous autosomal miRNAs between the male and female developing human lung. Additionally, the expression of some miRNAs are modified by age across the pseudoglandular stage in a sex-specific way. Some of these differences in miRNA expression may impact susceptibility to pulmonary disease later in life. Our results suggest that sex-specific miRNA expression during human lung development may be a potential mechanism to explain sex-specific differences in lung development and may impact subsequent disease susceptibility

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